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Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b

โœ Scribed by Akiko Tsumura; Tomohiro Hayakawa; Yuichi Kumaki; Shin-ichiro Takebayashi; Morito Sakaue; Chisa Matsuoka; Kunitada Shimotohno; Fuyuki Ishikawa; En Li; Hiroki R. Ueda; Jun-ichi Nakayama; Masaki Okano

Book ID
108731863
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
451 KB
Volume
11
Category
Article
ISSN
1356-9597

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Dynamic expression of de novo DNA methyl
Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
โœ Jian Feng; Hua Chang; En Li; Guoping Fan ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 889 KB

## Abstract To explore the role of DNA methylation in the brain, we examined the expression pattern of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the mouse central nervous system (CNS). By comparing the levels of Dnmt3a and Dnmt3b mRNAs and proteins in the CNS, we showed that Dnmt3b is det