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The Genomic Organization of the Fanconi Anemia Group A (FAA) Gene

✍ Scribed by Leonarda Ianzano; Maria d'Apolito; Marta Centra; Maria Savino; Orna Levran; Arleen D. Auerbach; Anne-Marie Cleton-Jansen; Norman A. Doggett; Jan C. Pronk; Alex J. Tipping; Rachel A. Gibson; Christopher G. Mathew; Scott A. Whitmore; Sinoula Apostolou; David F. Callen; Leopoldo Zelante; Anna Savoia

Book ID
115613790
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
125 KB
Volume
41
Category
Article
ISSN
0888-7543

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✍ Orna Levran; Norman A. Doggett; Arleen D. Auerbach πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 501 KB

Fanconi anemia (FA) is an autosomal recessive syndrome associated with hypersensitivity to DNA cross-linking agents and predisposition to neoplasia. Eight complementation groups (AH) have been described, but the only FA genes cloned so far are FAC and FAA. We have recently identified 40 different ge