Mutations of the Fanconi Anemia Group A Gene (FAA) in Italian Patients
β Scribed by Maria Savino; Leonarda Ianzano; Pierluigi Strippoli; Ugo Ramenghi; Araxy Arslanian; Gian Paolo Bagnara; Hans Joenje; Leopoldo Zelante; Anna Savoia
- Book ID
- 117852228
- Publisher
- American Society of Human Genetics
- Year
- 1997
- Tongue
- English
- Weight
- 373 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0002-9297
- DOI
- 10.1086/301632
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Fanconi anemia (FA) is an autosomal recessive syndrome associated with hypersensitivity to DNA cross-linking agents and predisposition to neoplasia. Eight complementation groups (AH) have been described, but the only FA genes cloned so far are FAC and FAA. We have recently identified 40 different ge
## Ponder Fanconi anemia (FA) is an autosomal recessive disorder associated with hypersensitivity to DNA cross-linking agents and bone marrow failure. At least four complementation groups have been defined, and the FA group C gene (FAC) has been cloned. We have screened 76 unrelated FA patients of