The Formation of 1,1'-(2-Deoxy-D-ribofuranosyl-2'-deoxy-D-ribofuranoside) Tetra-O-p-toluate in the Synthesis of 2-Deoxy-D-ribofuranosyl Nucleosides 1
✍ Scribed by Keller, F.; Bunker, J. E.; Brown, L. H.
- Book ID
- 126919078
- Publisher
- American Chemical Society
- Year
- 1966
- Tongue
- English
- Weight
- 465 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
## Abstract The dinucleoside phosphate __Π__~d~p__Π__~d~ (**4**) was synthesized from the monomers 1‐(5′‐__O__‐monomethoxytrityl ‐ 2′ ‐ deoxy ‐ β ‐ D ‐ ribofuranosyl) ‐ 2 (1 __H__) ‐ pyridone ((MeOTr) __Π__~d~, **2**) and 1‐(5′‐__O__‐phosphoryl‐3′‐__O__‐acetyl‐2′‐deoxy‐β‐D‐ribofuranosyl)‐(1__H__)‐p
## Abstract Convergent syntheses of the 9‐(3‐X‐2,3‐dideoxy‐2‐fluoro‐__β__‐D‐ribofuranosyl)adenines **5** (X=N~3~) and **7** (X=NH~2~), as well as of their respective __α__‐anomers **6** and **8**, are described, using methyl 2‐azido‐5‐__O__‐benzoyl‐2,3‐dideoxy‐2‐fluoro‐__β__‐D‐ribofuranoside (**4**