The reaction of [2-14C]-2 ,4-bis-O-(trimethylsilyl)uracil (2) with ~-~-acetyl-~-0-benzoyl-2-deoxy-2-fluoro-~-D-arabinofuranosyl bromide (3) yielded the 3-O-acety1-5-0-benzoyl nucleos e 4 which was hydrolyzed with methanolic ammonia to afford [ 2-feC]-T-( 2-deoxy-2fluoro-p-D-arabinofuranosy1)uracil (
✦ LIBER ✦
The synthesis of radiolabelled 1-(2′-Fluoro-2′-deoxy-β-D-ribofuranosyl)-uracil and 1-(2′-chloro-2′-deoxy-β-D-ribofuranosyl)uracil
✍ Scribed by Douglas N. Abrams; John R. Mercer; Edward E. Knaus; Leonard I. Wiebe
- Publisher
- Elsevier Science
- Year
- 1985
- Weight
- 680 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0020-708X
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