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The First Negishi Cross-Coupling Reaction of Two Alkyl Centers Utilizing a Pd−N-Heterocyclic Carbene (NHC) Catalyst †

✍ Scribed by Hadei, Niloufar; Kantchev, Eric Assen B.; O'Brie, Christopher J.; Organ, Michael G.


Book ID
120828035
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
72 KB
Volume
7
Category
Article
ISSN
1523-7060

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A User-Friendly, All-Purpose Pd-NHC (NHC
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

A User-Friendly, All-Purpose Pd–NHC (NHC
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## Abstract We have developed the first user‐friendly Negishi protocol capable of routinely cross‐coupling all combinations of alkyl and aryl centers. The use of an easily synthesized, air stable, highly active, well‐defined precatalyst PEPPSI‐IPr (**1**; PEPPSI=pyridine‐enhanced precatalyst prepar