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The effects of shear rate on the enzymatic activity of the tissue factor-factor VIIa complex

✍ Scribed by Cynthia H. Gemmell; Yale Nemerson; Vincent Turitto

Book ID
116035786
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
926 KB
Volume
40
Category
Article
ISSN
0026-2862

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✍ Daniel Kirchhofer; Yale Nemerson πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 637 KB

Tissue factor (TF), a transmembrane glycoprotein, functions as an essential activator of the serine protease factor Vlla. This enzymatic complex is considered to be the principal initiator of in vivo coagulation. Recent studies emphasize the role of the TF/Vlla complex in a number of pathophysiologi