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Aprotinin is a competitive inhibitor of the factor VIIa-tissue factor complex

โœ Scribed by J. Chabbat; P. Porte; M. Tellier; M. Steinbuch

Book ID
116086303
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
684 KB
Volume
71
Category
Article
ISSN
0049-3848

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Tissue factor (TF), a transmembrane glycoprotein, functions as an essential activator of the serine protease factor Vlla. This enzymatic complex is considered to be the principal initiator of in vivo coagulation. Recent studies emphasize the role of the TF/Vlla complex in a number of pathophysiologi