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The Effects of Ketoconazole on the Pharmacokinetics of Cyclosporine A in Cats

โœ Scribed by F. McAnulty Jonathan; G.L. Lensmeyer


Book ID
109135989
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
64 KB
Volume
28
Category
Article
ISSN
0161-3499

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โœ Tsutomu Kotegawa; Bart E. Laurijssens; Anna Liza B. Durol; David J. Greenblatt ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 114 KB ๐Ÿ‘ 2 views

To evaluate methodology for in vivo interaction studies of benzodiazepines (BZs) and ketoconazole (KCZ) in animal models, this study assessed the pharmacokinetics and electroencephalographic (EEG) effect of KCZ, and suitable dosage regimens of KCZ to maintain sufficiently high KCZ concentrations to