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The directed reduction of β-hydroxy ketones employing Me4NHB(OAc)3

✍ Scribed by David A. Evans; Kevin T. Chapman

Book ID
104219445
Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
265 KB
Volume
27
Category
Article
ISSN
0040-4039

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✦ Synopsis

The diastereoselective reduction of a range of acyclic Bhydroxy ketones with triacetoxyborohydride is described. In all cases, the anti 1,3-dial diastereomer is the principal product (eq I).

📜 SIMILAR VOLUMES

The directed reduction of β-hydroxy keto
The directed reduction of β-hydroxy ketones employing Me4NHB(OAc)3
✍ David A. Evans; Kevin T. Chapman 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 27 KB

Page 5939, paragraph 2, sentence 3 should read: The stereochemical information gained from these cases is consistent with a hydroxyl-mediated reduction, a mechanistic postulate first suggested by Saksena.Sa 5. (a) Saksena, A.