๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

The design and synthesis of a nonpeptide mimic of an immunosuppressing peptide

โœ Scribed by Michael Kahn; Bruce Devens


Book ID
104219156
Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
166 KB
Volume
27
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis


The synthesis and preliminary biological evaluation of a nonpeptide mimic of the immunosuppressant tripeptide (Lys-Pro-Arg) is described.


๐Ÿ“œ SIMILAR VOLUMES


Design and synthesis of functionalized t
โœ Kaori Sakurai; Daniel Kahne ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 630 KB

Oligosaccharides represent potentially useful scaffolds for the development of peptidomimetics. We report here the design and synthesis of functionalized trisaccharides modeled after an ฮฑ-helical 15-mer peptide region of p53 which binds to its cellular regulator MDM2. The trisaccharide scaffold was