✦ LIBER ✦

The complex basis underlying common fragile site instability in cancer

✍ Scribed by Efrat Ozeri-Galai; Assaf C. Bester; Batsheva Kerem

Book ID: 113933210
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 356 KB
Volume: 28
Category: Article
ISSN: 0168-9525
DOI: 10.1016/j.tig.2012.02.006

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Molecular characterization of FRAXB and

Molecular characterization of FRAXB and comparative common fragile site instability in cancer cells

✍ Martin F. Arlt; Diane E. Miller; David G. Beer; Thomas W. Glover 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 145 KB

## Abstract The common fragile site, FRA3B, has been shown to be a site of frequent homozygous deletions in some cancers, resulting in loss of expression of the associated __FHIT__ gene. It has been proposed that __FHIT__ is a tumor suppressor gene that is inactivated as a result of the instability

Interplay between genetic and epigenetic

Interplay between genetic and epigenetic factors governs common fragile site instability in cancer

✍ Ozeri-Galai, Efrat; Tur-Sinai, Michal; Bester, Assaf C.; Kerem, Batsheva 📂 Article 📅 2014 🏛 Springer 🌐 English ⚖ 402 KB

Mechanisms of Genomic Instabilities Unde

Mechanisms of Genomic Instabilities Underlying Two Common Fragile-Site-Associated Loci, PARK2 and DMD, in Germ Cell and Cancer Cell Lines

✍ Jun Mitsui; Yuji Takahashi; Jun Goto; Hiroyuki Tomiyama; Shunpei Ishikawa; Hiroy 📂 Article 📅 2010 🏛 American Society of Human Genetics 🌐 English ⚖ 990 KB

Collisions between Replication and Trans

Collisions between Replication and Transcription Complexes Cause Common Fragile Site Instability at the Longest Human Genes

✍ Anne Helmrich; Monica Ballarino; Laszlo Tora 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 528 KB

Activation of common fragile sites as a

Activation of common fragile sites as a possible cause of chromosome 8 instability in colorectal cancer

✍ Lena Brueckner; Manfred Schwab; Larissa Savelyeva 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 32 KB

Alterations in the common fragile site g

Alterations in the common fragile site gene Parkin in ovarian and other cancers

✍ Denison, Stacy R; Wang, Fang; Becker, Nicole A; Schüle, Birgitt; Kock, Norman; P 📂 Article 📅 2003 🏛 Nature Publishing Group 🌐 English ⚖ 220 KB