๐”– Bobbio Scriptorium
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The clinical role of prostate-specific membrane antigen (PSMA)

โœ Scribed by Sam S. Chang; Warren D.W. Heston


Book ID
117724132
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
381 KB
Volume
7
Category
Article
ISSN
1078-1439

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Prostate-specific membrane antigen (PSMA
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## Background: Prostate-specific membrane antigen (psma) is a glutamate carboxypeptidase that cleaves terminal carboxy glutamates from both the neuronal dipeptide n-acetylaspartylglutamate (naag) and gamma-linked folate polyglutamate. the prostate enzyme has activity in both the membrane and cytoso

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## Abstract Prostate specific membrane antigen (PSMA), is a unique membrane bound glycoprotein, which is overexpressed manifold on prostate cancer as well as neovasculature of most of the solid tumors, but not in the vasculature of the normal tissues. This unique expression of PSMA makes it an impo