The clinical role of prostate-specific membrane antigen (PSMA)
โ Scribed by Sam S. Chang; Warren D.W. Heston
- Book ID
- 117724132
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 381 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1078-1439
No coin nor oath required. For personal study only.
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We will review the evolution, benefits, and limitations of PSMA testing in the past, as well as its current and future value. Prostate cancer has been the most frequently diagnosed cancer and the second leading cause of cancer death in men in the United States. It has a wide spectrum of biological b
## Background: Prostate-specific membrane antigen (psma) is a glutamate carboxypeptidase that cleaves terminal carboxy glutamates from both the neuronal dipeptide n-acetylaspartylglutamate (naag) and gamma-linked folate polyglutamate. the prostate enzyme has activity in both the membrane and cytoso
## Abstract Prostate specific membrane antigen (PSMA), is a unique membrane bound glycoprotein, which is overexpressed manifold on prostate cancer as well as neovasculature of most of the solid tumors, but not in the vasculature of the normal tissues. This unique expression of PSMA makes it an impo