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Enzymatic activation of prodrugs by prostate-specific membrane antigen (PSMA)

Book ID
117659446
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
141 KB
Volume
38
Category
Article
ISSN
0959-8049

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Prostate-specific membrane antigen (PSMA
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## Background: Prostate-specific membrane antigen (psma) is a glutamate carboxypeptidase that cleaves terminal carboxy glutamates from both the neuronal dipeptide n-acetylaspartylglutamate (naag) and gamma-linked folate polyglutamate. the prostate enzyme has activity in both the membrane and cytoso