Interleukin 4 inhibits murine osteoclast
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Atsushi Shioi; Steven L. Teitelbaum; F. Patrick Ross; Howard G. Welgus; Hidenori
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Article
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1991
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John Wiley and Sons
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English
β 593 KB
Interleukin 4 (IL-4) is a product of activated T cells and mast cells with effects on immunologic and hematopoietic processes. We now report that IL-4 inhibits the formation of osteoclasts from murine bone marrow <:ells cocultured with stromal cells. Numerous (3,000-4,000 cells/2 cm2) tartrate-resis