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Tandutinib inhibits FMS receptor signalling, and macrophage and osteoclast formation in vitro

✍ Scribed by Brownlow, N; Vaid, M; Dibb, N J

Book ID
110058595
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
95 KB
Volume
22
Category
Article
ISSN
0887-6924

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Interleukin 4 (IL-4) is a product of activated T cells and mast cells with effects on immunologic and hematopoietic processes. We now report that IL-4 inhibits the formation of osteoclasts from murine bone marrow <:ells cocultured with stromal cells. Numerous (3,000-4,000 cells/2 cm2) tartrate-resis