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The C-terminal domain of the adenomatous polyposis coli (Apc) protein is involved in thyroid morphogenesis and function

✍ Scribed by Atsushi Yokoyama; Ryuji Nomura; Masafumi Kurosumi; Atsushi Shimomura; Takanori Onouchi; Akiko Iizuka-Kogo; Ron Smits; Naohisa Oda; Riccardo Fodde; Mitsuyasu Itoh; Takao Senda


Book ID
113053235
Publisher
Springer
Year
2011
Tongue
English
Weight
455 KB
Volume
44
Category
Article
ISSN
0918-4287

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A decrease in the intracellular concentrations of the transcripts for some tumor suppressor genes has been found during murine lung tumorigenesis; for p15 INK4b and p16 INK4a , this was due to homozygous deletions. We report here a decrease in the mRNA levels of the mutated in colorectal cancer (Mcc