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The binding of the benzo/a/pyrene metabolites to the DNA of isolated rat liver nuclei and nuclear matrix

✍ Scribed by W. Baer-Dubowska; K. Alexandrov


Book ID
115778002
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
158 KB
Volume
34
Category
Article
ISSN
0006-2952

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Rat liver microsome-mediated binding of
✍ M. H. Thompson; H. W. S. King; M. R. Osborne; P. Brookes πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 French βš– 422 KB πŸ‘ 1 views

## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy