𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The asymmetric synthesis of γ-substituted glutamic acid derivatives via a glutamic acid γ-enolate synthon

✍ Scribed by Marco Del Bosco; Andrew N.C. Johnstone; Giorgia Bazza; Stefania Lopatriello; Michael North

Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
706 KB
Volume
51
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Enantioselective syntheses of α-substitu
Enantioselective syntheses of α-substituted glutamic acids and α,γ-disubstituted glutamic acids by an asymmetric Strecker reaction
✍ Dawei Ma; Guozhi Tang; Hongqi Tian; Guixiang Zou 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 199 KB

The Strecker reaction of the product from the treatment of the sodium salt of 7-keto acids with (S)-phenylglycinol followed by heating the products to 200 °C gives the bicyclic lactones 9 and 10. Alkylation of 9 provides 11 and 12. Both 9b and lla are converted into the corresponding substituted gl