The association between headache and Val158Met polymorphism in the catechol–O–methyltransferase gene: the HUNT Study
✍ Scribed by K. Hagen; E. Pettersen; L. J. Stovner; F. Skorpen; J.-A. Zwart
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 50 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1129-2369
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Objective Genetic polymorphisms of the noradrenergic pathway can be factors to predict the effect of antidepressants when their pharmacological mechanisms of action include the noradrenergic system. The purpose of the present study was to determine whether the tyrosine hydroxylase (
## Abstract ## Background: The A‐allele of the catechol‐__O__‐methyltransferase (__COMT__) Val158Met polymorphism is associated with decreased enzymatic activity and higher dopamine availability. ## Methods: We studied 219 patients with PD who were free of dyskinesias at baseline and underwent t