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The catechol-O-methyltransferase Val(108/158)Met polymorphism affects antidepressant response to paroxetine in a naturalistic setting

✍ Scribed by Francesco Benedetti; Cristina Colombo; Adele Pirovano; Elena Marino; Enrico Smeraldi


Publisher
Springer
Year
2008
Tongue
English
Weight
130 KB
Volume
203
Category
Article
ISSN
0033-3158

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Catechol-O-methyltransferase val108/158m
✍ Ari Illi; Olli Kampman; Kari Hänninen; Sami Anttila; Kari M. Mattila; Heikki Kat 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 83 KB

## Abstract Catechol‐O‐methyltransferase (COMT) gene has been investigated as a possible candidate gene in schizophrenia. The most studied polymorphism has been the functional val108/158met polymorphism of this COMT gene. There is also some evidence that this polymorphism could be related to drug r