The authors thank all patients and blood donors who participated in this study and gratefully acknowledge Dr. H. Olthuis and his staff at the Red Cross Blood Bank of Nijmegen for collecting blood samples from the donors.
The Association Between Glutathione S-Transferase P1 Genotype and Plasma Level in Head and Neck Cancer
β Scribed by Willem P. A. Kelders; Michael B. Oude Ophuis; Hennie M. J. Roelofs; Wilbert H. M. Peters; Johannes J. Manni
- Book ID
- 110083962
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 96 KB
- Volume
- 112
- Category
- Article
- ISSN
- 0023-852X
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## Abstract ## Background. Factors determining the individual susceptibility to head and neck squamous cell carcinoma (HNSCC) are still largely unknown. An imbalance between enzymes involved in the toxification and detoxification of (pre)βcarcinogens closely related to HNSCC, which may appear duri
Background. We sought to evaluate the estimated risk of GSTM1 null genotype and squamous cell carcinoma of the head and neck (SCCHN). Methods. The studies done so far for GSTM1 null genotype as a risk factor associated with head and neck cancer are not conclusive and have shown conflicting results.