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The anti-T cell monoclonal antibody 9.3 (Anti-CD28) provides a helper signal and bypasses the need for accessory cells in T Cell activation with immobilized anti-CD3 and mitogens

✍ Scribed by Miren L. Baroja; Katrien Lorre; Frieda Van Vaeck; Jan L. Ceuppens


Book ID
113134327
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
965 KB
Volume
120
Category
Article
ISSN
0008-8749

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✍ RenΓ© A. W. Van Lier; Miranda Brouwer; Lueien A. Aarden πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 654 KB

Monoclonal antibodies (mAb) directed against the T cell differentiation antigen CD28 (Tp44) induce proliferation of resting T lymphocytes in the presence of phorbol esters. Moreover, it has been reported that such antibodies augment and sustain T cell proliferation induced by soluble antigens, phyto