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The amygdala mediates the impairing effect of the selective κ-opioid receptor agonist U-50,488 on memory in CD1 mice

✍ Scribed by Claudio Castellano; Vincenzo Libri; Martine Ammassari-Teule

Book ID
118394958
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
452 KB
Volume
30
Category
Article
ISSN
0166-4328

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## Opioid receptor agonists (e.g.,488) increase the locomotor activity of preweanling rats, while the same drugs depress the locomotor activity of adults. Curiously, direct stimulation of dopamine (DA) D 2 -like receptors fully attenuates the U-50,488-induced locomotor activity of preweanling rats