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Effect of dizocilpine (MK-801) on analgesia and tolerance induced by U-50,488H, a κ-opioid receptor agonist, in the mouse

✍ Scribed by Hemendra N. Bhargava; Sanjay N. Thorat


Book ID
115804989
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
521 KB
Volume
649
Category
Article
ISSN
0006-8993

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The effect of ℵ-opioid agonist U-50, 488
✍ Masuo Ohno; Tsuneyuki Yamamoto; Hiroaki Araki; Showa Ueki 📂 Article 📅 1987 🏛 Springer 🌐 English ⚖ 483 KB

The effect of a selective kappa-opioid agonist, U-50, 488H, on wet-dog shaking (WDS) induced by hippocampal stimulation was investigated and compared with that produced by morphine. U-50, 488H, as well as morphine, inhibited the appearance of WDS in a dose-dependent manner. U-50, 488H was approximat