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Effects of the κ-opioid receptor agonist U-50,488 on morphine-induced place preference conditioning in the developing rat

✍ Scribed by Carlos A. Bolanos; Gabrielle M. Garmsen; Mark A. Clair; Sanders A. McDougall


Book ID
117098849
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
794 KB
Volume
317
Category
Article
ISSN
0014-2999

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## Opioid receptor agonists (e.g.,488) increase the locomotor activity of preweanling rats, while the same drugs depress the locomotor activity of adults. Curiously, direct stimulation of dopamine (DA) D 2 -like receptors fully attenuates the U-50,488-induced locomotor activity of preweanling rats