The absolute configuration of the enantiomers of glutethimide and aminoglutethimide
β Scribed by N. Finch; R. Dziemian; J. Cohen; B. G. Steinetz
- Book ID
- 112732797
- Publisher
- Springer
- Year
- 1975
- Tongue
- English
- Weight
- 218 KB
- Volume
- 31
- Category
- Article
- ISSN
- 1420-682X
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The pure enantiomers of felodipine, 1, have been synthesized by chromatographic separation of diastereomeric esters with (R)-l-(p-toluenesulfonyl)-3-trityloxypropan-2-ol, 3, as an easily removable chiral auxiliary. Absolute configurations have been deduced via X-ray crystallography on a (R)-mandelic