## Abstract Nasopharyngeal carcinoma, a malignancy associated closely with EpsteinβBarr virus (EBV), is prevalent among Chinese of Southern China origin. Epidemiological studies indicate a high prevalence of EBV in Asia with viral isolates having typical characteristics of the putative viral oncoge
The 30-bp deletion variant: a polymorphism of latent membrane protein 1 prevalent in endemic and non-endemic areas of nasopharyngeal carcinomas in China
β Scribed by Xiao-Shi Zhang; Kun-Hua Song; Hai-Qiang Mai; Wei-Hua Jia; Bing-Jian Feng; Jian-Chuan Xia; Ru-Hua Zhang; Li-Xi Huang; Xing-Juan Yu; Qi-Sheng Feng; Ping Huang; Jian-Jing Chen; Yi-Xin Zeng
- Book ID
- 117467134
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 166 KB
- Volume
- 176
- Category
- Article
- ISSN
- 0304-3835
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A specific variant of Epstein-Barr virus (EBV) with a 30-bp deletion in the C-terminal region of the LMP1 gene has been found in some EBV-associated malignancies. To better understand the tumorigenic role of this LMP1 variant, we used PCR and sequencing to examine the LMP1 gene in 38 EBVassociated c
Epstein-Barr virus in Hodgkin's disease: frequency of a 30-bp deletion in the latent membrane protein 1 (LMP-