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Epstein-Barr virus in Hodgkin's disease: frequency of a 30-bp deletion in the latent membrane protein (LMP-1) oncogene in South African patients

โœ Scribed by M. Fadiel Essop; Mark Engel; Pauline Close; Colin Sinclair-Smith; Gorm Pallesen


Publisher
John Wiley and Sons
Year
1999
Tongue
French
Weight
58 KB
Volume
84
Category
Article
ISSN
0020-7136

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โœฆ Synopsis


Epstein-Barr virus in Hodgkin's disease: frequency of a 30-bp deletion in the latent membrane protein 1 (LMP-


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โœ Suet Y. Leung; Siu T. Yuen; Lap P. Chung; Annie S.Y. Chan; Maria P. Wong ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 70 KB ๐Ÿ‘ 1 views

A specific variant of Epstein-Barr virus (EBV) with a 30-bp deletion in the C-terminal region of the LMP1 gene has been found in some EBV-associated malignancies. To better understand the tumorigenic role of this LMP1 variant, we used PCR and sequencing to examine the LMP1 gene in 38 EBVassociated c