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TFIIH Kinase Places Bivalent Marks on the Carboxy-Terminal Domain of RNA Polymerase II

✍ Scribed by Md. Sohail Akhtar; Martin Heidemann; Joshua R. Tietjen; David W. Zhang; Rob D. Chapman; Dirk Eick; Aseem Z. Ansari


Book ID
116754693
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
699 KB
Volume
34
Category
Article
ISSN
1097-2765

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Cdc2 kinase triggers the entry of mammalian cells into mitosis, the only cell cycle phase in which transcription is globally repressed. We show here that Cdc2 kinase phosphorylates components of the RNA polymerase II transcription machinery including the RNA polymerase II carboxy-terminal repeat dom