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The Medicago CDKC;1-CYCLINT;1 kinase complex phosphorylates the carboxy-terminal domain of RNA polymerase II and promotes transcription

✍ Scribed by Katalin Fülöp; Aladàr Pettkó-Szandtner; Zoltán Magyar; Pál Miskolczi; Éva Kondorosi; Dénes Dudits; László Bakó

Book ID
110867228
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
281 KB
Volume
42
Category
Article
ISSN
0960-7412

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Cdc2 kinase triggers the entry of mammalian cells into mitosis, the only cell cycle phase in which transcription is globally repressed. We show here that Cdc2 kinase phosphorylates components of the RNA polymerase II transcription machinery including the RNA polymerase II carboxy-terminal repeat dom