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Taxol synthesis: Synthesis of A-ring and a methodology for substituted cyclohexadienes

✍ Scribed by J.S. Jadav; Dale Srinivas

Publisher: Elsevier Science
Year: 1997
Tongue: French
Weight: 188 KB
Volume: 38
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(97)10038-7

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✦ Synopsis

A fully functionalised synthesis of taxol A-ring, through Michael/Wittig reaction and regioselective opening epoxide as key steps and also a methodology for substituted cyclohexadienes through tandem Michael/WRtig reaction is described.

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