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Targeting Histone Deacetylases for the Treatment of Huntington's Disease

✍ Scribed by Steven G. Gray


Book ID
118076733
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
232 KB
Volume
16
Category
Article
ISSN
1755-5930

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Targeting histone deacetylases for the t
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## Abstract Histone deacetylases (HDACs) are involved in chromatin remodeling and modification of nonhistone transcription regulatory proteins, thus modulating the expression of genes important for complex biological events. Dysregulation of HDACs and aberrant chromatin acetylation and deacetylatio