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Targeting histone deacetylases for the treatment of disease

✍ Scribed by M. W. Lawless; S. Norris; K. J. O’Byrne; S. G. Gray

Book ID
114778552
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2009
Tongue
English
Weight
623 KB
Volume
13
Category
Article
ISSN
1582-1838

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## Abstract Histone deacetylases (HDACs) are involved in chromatin remodeling and modification of nonhistone transcription regulatory proteins, thus modulating the expression of genes important for complex biological events. Dysregulation of HDACs and aberrant chromatin acetylation and deacetylatio