## Abstract A number of histologic variants of wellโdifferentiated papillary carcinoma have been found to be associated with more aggressive tumor behavior. Tall cell, columnar cell, diffuse sclerosing, solid/trabecular, and insular variants of wellโdifferentiated papillary thyroid cancer are all p
Tall cell variant: An aggressive form of papillary thyroid carcinoma
โ Scribed by STEPHEN PRENDIVILLE; KENNETH D. BURMAN; MATTHEW D. RINGEL; BARRY M. SHMOOKLER; ZIAD E. DEEB; KATHERINE WOLFE; NORIO AZUMI; LEONARD WARTOFSKY; ROY B. SESSIONS
- Book ID
- 117398759
- Publisher
- SAGE Publications
- Year
- 2000
- Tongue
- English
- Weight
- 107 KB
- Volume
- 122
- Category
- Article
- ISSN
- 0194-5998
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๐ SIMILAR VOLUMES
## Background: The tall cell variant of papillary carcinoma of the thyroid (tcv) is characterized by the proliferation of oxyphilic, tall, columnar cells with a height-to-width ratio of at least 2:1. tcv exhibits more aggressive clinical behavior than conventional thyroid papillary carcinoma (cpc).
## Abstract ## BACKGROUND Tall cell variant papillary carcinoma of the thyroid demonstrates unusually aggressive clinical behavior compared with the usual form of papillary thyroid carcinoma. The protoโoncogene cโ__met__ encodes a tyrosine kinase receptor known to influence cell invasion. This cur