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Tall cell variant of papillary thyroid carcinoma with foci of columnar cell component

โœ Scribed by M. Shimizu; Mitsuyoshi Hirokawa; Toshiaki Manabe


Book ID
106118792
Publisher
Springer
Year
1999
Tongue
English
Weight
191 KB
Volume
434
Category
Article
ISSN
1432-2307

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Columnar cell variant of papillary carcinoma (CCV-PC) thyroid is a rare and aggressive tumor composed of tall columnar cells that form papillae, glands and solid structures. This paper describes fine needle aspiration (FNA) cytologic features in a case of CCV-PC occurring in the right thyroid lobe o

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## Background: The tall cell variant of papillary carcinoma of the thyroid (tcv) is characterized by the proliferation of oxyphilic, tall, columnar cells with a height-to-width ratio of at least 2:1. tcv exhibits more aggressive clinical behavior than conventional thyroid papillary carcinoma (cpc).

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## Abstract ## BACKGROUND Tall cell variant papillary carcinoma of the thyroid demonstrates unusually aggressive clinical behavior compared with the usual form of papillary thyroid carcinoma. The protoโ€oncogene cโ€__met__ encodes a tyrosine kinase receptor known to influence cell invasion. This cur