## Background: The tall cell variant of papillary carcinoma of the thyroid (tcv) is characterized by the proliferation of oxyphilic, tall, columnar cells with a height-to-width ratio of at least 2:1. tcv exhibits more aggressive clinical behavior than conventional thyroid papillary carcinoma (cpc).
Breast Tumor Resembling the Tall Cell Variant of Papillary Thyroid Carcinoma
✍ Scribed by Sing Yun Chang; David M. Fleiszer; Benoît Mesurolle; Mona El Khoury; Atilla Omeroglu
- Book ID
- 109079858
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 352 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1075-122X
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## Abstract ## BACKGROUND Tall cell variant papillary carcinoma of the thyroid demonstrates unusually aggressive clinical behavior compared with the usual form of papillary thyroid carcinoma. The proto‐oncogene c‐__met__ encodes a tyrosine kinase receptor known to influence cell invasion. This cur
Cytologic reports of the aggressive tall-cell and diffuse sclerosing variants of papillary carcinoma have emphasized features such as tall and large cells, increased nuclear size, nuclear pleomorphism, intranuclear pseudoinclusions, three-dimensional tissue fragments, squamous-like cells, and dense