t(8;13) (p11;q12) translocation in a myeloproliferative disorder associated with a T-cell non-Hodgkin lymphoma
โ Scribed by J. Leslie; T. Barker; M. Glancy; B. Jennings; J. Pearson
- Book ID
- 114713652
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 333 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0007-1048
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Fourteen cases of an atypical myeloproliferative disorder associated with consistent translocations involving 8p11-12 have previously been described. A t(8;13)(p11;q11-12) was the most common, but variant t(8;9)(p11-12;q32-34) and t(6;8)(q27;p12) were also reported. Here we have used a series of yea
An unusual hematologic neoplasia has been described recently in which the predominant clinical features include T-cell lymphoma, myeloid hyperplasia, and eosinophilia. The multilineage involvement in this disorder suggests transformation of a primitive stem cell. Abnormal karyotypes have been descri