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A novel t(1;8)(q25;p11.2) translocation associated with 8p11 myeloproliferative syndrome

✍ Scribed by Chikamasa Yoshida; Makoto Takeuchi; Yoshito Sadahira


Book ID
108677414
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
529 KB
Volume
156
Category
Article
ISSN
0007-1048

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8p11 myeloproliferative syndrome with a
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## Abstract 8p11 myeloproliferative syndrome (EMS) is a clinical‐pathologic entity characterized by rearrangements involving the __FGFR1__ gene, which encodes a receptor tyrosine kinase. These rearrangements invariably lead to aberrant fusion proteins in which the kinase activity is constitutively