## Abstract The syntheses of four analogues of oxytocine are described: one with a phenylalanyl residue replacing the isoleucyl residue, one with a leucyl residue replacing the isoleucyl residue, one with a valyl residue replacing the isoleucyl residue, and one with a glutaminyl residue replacing t
Synthèse d'analogues structuraux de la bradykinine
✍ Scribed by St. Guttmann; R. A. Boissonnas
- Publisher
- John Wiley and Sons
- Year
- 1961
- Tongue
- German
- Weight
- 790 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
The synthesis of the four following analogues of Bradykinine is described in detail:H‐Arg‐Pro‐Gly‐Phe‐Ser‐Pro‐Phe‐Arg‐OH, H‐Arg‐Pro‐Pro‐Phe‐Gly ‐Ser ‐Phe‐Arg‐OH, H‐Arg‐Pro‐Gly‐Pro‐Phe‐Ser‐Phe‐Arg‐OH and H‐Arg‐Pro‐Gly‐Phe‐Ser‐Phe‐Arg‐OH. The first of these peptides exhibited a small bradykinin‐like activity. The three others were inactive.
📜 SIMILAR VOLUMES
## Abstract An improved synthesis of Bradykinin is described. N‐CBO‐G‐tosyl‐L‐arginyl‐L‐prolyl‐L‐prolyl‐glycine __p__‐nitrophenyl ester and L‐phenylalanyl‐L‐seryl‐L‐prolyl‐L‐phenylalanyl‐G‐tosyl‐L‐arginine are prepared and condensed together to N‐CBO‐G‐tosyl‐L‐arginyl‐L‐prolyl‐L‐prolyl‐glycyl‐L‐phe
## 5) 2-Methylamino-5-phe9ayl-7-tvifluormethyl-3H-1, 4-benzodiazepin-4-oxid (XXIII) . 500 mg Chinazolin X X wurden 5 Std. bei Raumtemperatur mit 10 ml einer 40-proz. Usung von Methylamin in Methanol stehengelassen, wobei eine klare Liisung entstand. Das in gewohnter Weise durch Atherextraktion ge