Ul'IM~\ R'I' Rac. 2-dehydro-emetine (XV) and rac. 2-dehydro-isoemetine (XVI) have been synthcsizcd in fivc steps and in good yicld from 2-oxo-3-ethyl-9,10-dimethoxy-l, 2,3, 4,6, . Homologues and analogues of XV and XVI with other substituents have been obtained in the same way. Rac. 2-dchydro-emeti
Synthèse d'analogues structuraux de l'oxytocine
✍ Scribed by R. A. Boissonnas; St. Guttmann; P.-A. Jaquenoud; J.-P. Waller
- Publisher
- John Wiley and Sons
- Year
- 1956
- Tongue
- German
- Weight
- 496 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The syntheses of four analogues of oxytocine are described: one with a phenylalanyl residue replacing the isoleucyl residue, one with a leucyl residue replacing the isoleucyl residue, one with a valyl residue replacing the isoleucyl residue, and one with a glutaminyl residue replacing the asparaginyl residue.
📜 SIMILAR VOLUMES
**Synthesis of Evernin** Two syntheses of the depside evernin **6** are described. Condensation of methyl acetoacetate and methyl crotonate followed by aromatization and reduction with __Raney__‐Ni led to methyl orsellinate **(3)**. The condensation of everninic acid **(4)**, obtained by partial me
**Synthesis of Eriodermin** The total synthesis of eriodermin (=2,7‐dichloro‐4‐formyl 3‐hydroxy‐8‐methoxy‐1,6‐dimethyl‐11__H__‐dibenzo[__b__,__e__] [1,4]dioxepin‐11‐one) is described.
posssdent des structures tr&s diffgrentes de celle de l'oxytocine par suite de l'agrandissement du cycle disulfure. Elles sont toutes deux ddnuies d'activitd oxytocique.