Synthetic Mimetics of the CD4 Binding Site of HIV-1 gp120 for the Design of Immunogens
β Scribed by Raimo Franke; Tatjana Hirsch; Heike Overwin; Jutta Eichler
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 235 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
LAV44 and LAV15 (lymphadenopathy-associated virus) peptides of the CD4-binding region of gp 120 per se bind to the CD4 receptor (Reed and Kinzel, Biochemistry 30: 4521-4528, 1991; Lasky et al., Cell 50:975-985, 1987). Depending on the environment, the LAV peptides exhibit the ability to switch coope
Pseudoprolines (YPro) have been introduced recently as synthetic proline analogues readily obtained by cyclocondensation of the amino acids cysteine, threonine, or serine with aldehydes or ketones. [1] Their application as structure-disrupting, solubilizing protecting groups in solid-phase peptide s
Supporting information for this article is available on the WWW under http://dx.doi.org/10.1002/cmdc.201000222: I. MALDI-TOF MS and RP-HPLC analysis for all reported peptides; II. Competition ELISAs, antiviral assays, and SPR sensorgrams for all reported peptides.