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Synthesis, Stereochemistry, and Biological Activity of 1α,23,25-Trihydroxy-24-oxovitamin D 3 , a Major Natural Metabolite of 1α,25-Dihydroxyvitamin D 3†

✍ Scribed by Lee, Nancy E.; Reddy, G. Satyanarayana; Brown, Alex J.; Williard, Paul G.


Book ID
126773255
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
234 KB
Volume
36
Category
Article
ISSN
0006-2960

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Stereoselective synthesis of (25R)-25,26
✍ Sachiko Yamada; Keiko Nakayama; Hiroaki Takayama; Toshimasa Shinki; Tatsuo Suda 📂 Article 📅 1984 🏛 Elsevier Science 🌐 French ⚖ 256 KB

25l?)-25,26-Dihydroxy-23-oxovitamin D3 was synthesized efficiently and stereoselectively, and it was converted enzymatically to (25R\_)-lcr,25,26-trihydroxy-23-oxovitamin D3, a putative metabolite of la,25\_dihydroxyvitamin D3. The spectral and chemical properties of (25R&25,26-dihydroxy-23-oxovitam