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Synthesis and determination of the stereochemistry of 23,25-dihydroxy-24-oxovitamin D3, a major metabolite of 24(R),25-dihydroxyvitamin D3

โœ Scribed by Yamada, Sachiko; Yamamoto, Keiko; Ino, Eiichi; Sakaida, Kazumasa; Takayama, Hiroaki; Shinki, Toshimasa; Suda, Tatsuo; Iitaka, Yoichi; Itai, Akiko


Book ID
127265273
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
776 KB
Volume
28
Category
Article
ISSN
0006-2960

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Stereoselective synthesis of (25R)-25,26
โœ Sachiko Yamada; Keiko Nakayama; Hiroaki Takayama; Toshimasa Shinki; Tatsuo Suda ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 256 KB

25l?)-25,26-Dihydroxy-23-oxovitamin D3 was synthesized efficiently and stereoselectively, and it was converted enzymatically to (25R\_)-lcr,25,26-trihydroxy-23-oxovitamin D3, a putative metabolite of la,25\_dihydroxyvitamin D3. The spectral and chemical properties of (25R&25,26-dihydroxy-23-oxovitam