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Synthesis and biological activities of the two C(23) epimers of 1α,23,25-trihydroxy-24-oxo-19-nor-vitamin D3: novel analogs of 1α,23(S),25-trihydroxy-24-oxo-vitamin D3, a natural metabolite of 1α,25-dihydroxyvitamin D3

✍ Scribed by Nancy E Lee; Paul G Williard; Alex J Brown; Moray J Campbell; H.Phillip Koeffler; Sara Peleg; D.Sunita Rao; G.Satyanarayana Reddy


Book ID
117214184
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
503 KB
Volume
65
Category
Article
ISSN
0039-128X

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Stereoselective synthesis of (25R)-25,26
✍ Sachiko Yamada; Keiko Nakayama; Hiroaki Takayama; Toshimasa Shinki; Tatsuo Suda 📂 Article 📅 1984 🏛 Elsevier Science 🌐 French ⚖ 256 KB

25l?)-25,26-Dihydroxy-23-oxovitamin D3 was synthesized efficiently and stereoselectively, and it was converted enzymatically to (25R\_)-lcr,25,26-trihydroxy-23-oxovitamin D3, a putative metabolite of la,25\_dihydroxyvitamin D3. The spectral and chemical properties of (25R&25,26-dihydroxy-23-oxovitam