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Synthesis, Purification and Crystallization of Guanine-rich RNA Oligonucleotides

โœ Scribed by Baocheng Pan; Ke Shi; Muttaiya Sundaralingam

Book ID
101975583
Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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The protection of uracil and 2-E-acyl guanine residues with 4-G-phenyl [or 4-c-(2,4dimethylphenyl)] and 6-g-(Z-nitrophenyl) groups as in 7a [or 7bl and 2, respectively, is described. These g-aryl protecting groups, which appearto withstand the usual conditions of oligonucleotide synthesis, may rea