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Synthesis of Δ4-3-oxo-steroids labelled specifically at the 6β -position

✍ Scribed by P. Toft; A. J. Liston; A. Y. Viau

Publisher
John Wiley and Sons
Year
1973
Tongue
French
Weight
159 KB
Volume
9
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

[6β‐^2^H] Testosterone and [6β‐^3^H] Testosterone were each synthesized in good yield in three steps: Treatment of 5a, 6a‐ epoxy‐3, 3‐ethylene‐dioxyandrostan ‐17β‐ol with labelled lithium aluminum hydride is followed by deacetalation and dehydration under carefully controlled basic conditions.

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