6-aminolevulinic acid-4J4C was built up from phthalimide using KI4CN as the radioactive starting material. This method avoids the Iess practical synthesis via g1ycineJ4C and its condensation with phthalic anhydride to aflord phthalylglycine-l-14C whose yield, based on K-'4CN, is thus considerably im
Synthesis of δ-[15N]aminolevulinic acid hydrochloride
✍ Scribed by Katsumi Iida; Yuki Takao; Tomoe Ogai; Masahiro Kajiwara
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- French
- Weight
- 228 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract 5‐[4‐^13^C,^15^N]‐ and 5‐[5‐^13^C,^15^N]Aminolevulinic acid (ALA) were simply synthesized in four steps by the condensation of [1‐^13^C,^15^N]‐ or [2‐^13^C,^15^N]glycine, respectively, with phthalic anhydride, followed by conversion to the chloride, coupling reaction with a three‐carbon
## Abstract The synthesis of [^15^N]‐ labelled procaine hydrochloride, using (^15^NH~4~)~2~SO~4~ as starting isotopically labelled material, is presented. The experimental procedure is an adaptation of the synthesis methods for the corresponding unlabelled compounds.
## Abstract This report presents an efficient synthesis of [^15^N]t‐butylamine hydrochloride. Acylation of [^15^N]ammonia with pivaloyl chloride provided [^15^N]pivalamide, this was converted to benzyl [^15^N]N‐t‐butylcarbamate through a Hofmann rearrangement. Hydrogenolysis of benzyl [^15^N]N‐t‐bu