## Abstract Efficient methods for synthesising L‐[methy‐ ^13^C]methionine from [^13^C]iodomethane and L‐methionine, and L‐[3,4‐^13^C~2~] methionine from [^13^C~2~]ethene, are described; the preparation of [3,3‐^2^H~2~]methionine and [2,3,3‐^2^H~3~]methionine from methionine by an exchange method is
Synthesis of ubiquinones-3 specifically labelled with 13C at C(5)- or C(6)- positions
✍ Scribed by Claude Boullais; Jacques Breton; Eliane Nabedryk; Charles Mioskowski
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 445 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0040-4020
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## Abstract The condensation of ethyl acetoacetate‐^13^C~4~ and ethyl bromoacetate‐^13^C~2~ afforded, in seven steps, (1,2,3,4,5‐^13^C~5~) 5‐(diethylphosphono)‐2‐pentanone ethylene ketal 9. The reaction of this labelled compound with 7‐[[(1,1‐dimethylethyl)‐dimethylsilyl]oxy]‐1,6,6a,7,8,9,9a, 9b‐oc
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