Synthesis of two potential heterocyclic amine food mutagens
✍ Scribed by Mary J. Tanga; Joseph A. Kozocas; Todd K. Tochimoto
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2008
- Tongue
- English
- Weight
- 248 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
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The syntheses of two potential food mutagens formed during cooking, 2‐amino‐3,6,7‐trimethyl‐3__H__‐imidazo[4,5‐b]pyridine (1) and 2‐amino‐3,6,7‐trimethyl‐3__H__‐imidazo[4,5‐c]pyridine (2), are described.
📜 SIMILAR VOLUMES
## Abstract The syntheses of the potential heterocyclic amine food mutagens l,4,6‐trimethyl‐2‐aminoimidazo[4,5‐__c__]‐pyridine and 1,5,7‐trimethyl‐2‐aminoimidazo[4,5‐__b__]pyridine are described.
Chlorophyllin (CHL), a water-soluble derivative of chlorophyll, forms molecular complexes with heterocyclic amine mutagens in vitro. In a previous study : Environ Mol Mutagen, 22: 164-1711, we observed an inverse correlation between the binding constants of several mutagen-CHL complexes and the anti